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however, the pattern of transmission varies among countries.

As of 2014, most HIV transmission in the United States occurred among men who had sex with men (83% of new HIV diagnoses among males aged 13 and older and 67% of total new diagnoses).

During primary infection, the level of HIV may reach several million virus particles per milliliter of blood. This weakens the immune system and allows opportunistic infections.

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Lentiviruses share many morphological and biological characteristics.In low-income countries, the risk of female-to-male transmission is estimated as 0.38% per act, and of male-to-female transmission as 0.30% per act; the equivalent estimates for high-income countries are 0.04% per act for female-to-male transmission, and 0.08% per act for male-to-female transmission.Sexual assault is also believed to carry an increased risk of HIV transmission as condoms are rarely worn, physical trauma to the vagina or rectum is likely, and there may be a greater risk of concurrent sexually transmitted infections.Many species of mammals are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period.Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses.

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